Data set name: GSE89

Brief description:

The stage of bladder carcinoma at diagnosis is important in determining the disease course of a patient. Based on gene expression values we tried to distinguish between 40 well characterized bladder tumor samples.

Platform: Affymetrix GeneChip Human Full Length Array HuGeneFL

Diagnostic classes:

- tumor stage T2-T4 (T2+): 10 examples (25.0%)

- tumor stage Ta (Ta): 19 examples (47.5%)

- tumor stage T1 (T1): 11 examples (27.5%)

Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):

Classification accuracy: 90.00%

Area under curve (AUC): 0.969

	Score: 99.93% Genes: Z19554_s_at: vimentin, VIM M57731_s_at: chemokine (C-X-C motif) ligand 2, CXCL2 M55998_s_at: collagen, type I, alpha 1, COL1A1 U90549_at: high mobility group nucleosomal binding domain 4, HMGN4 U07231_at: G-rich RNA sequence binding factor 1, GRSF1 U19765_at: zinc finger protein 9 (a cellular retroviral nucleic acid binding protein), ZNF9 L19686_rna1_at: macrophage migration inhibitory factor (glycosylation-inhibiting factor), MIF X68561_at: Sp4 transcription factor, SP4
	Score: 99.70% Genes: Z19554_s_at: vimentin, VIM M55998_s_at: collagen, type I, alpha 1, COL1A1 U90549_at: high mobility group nucleosomal binding domain 4, HMGN4 S77393_at: Kruppel-like factor 3 (basic), KLF3 L19686_rna1_at: macrophage migration inhibitory factor (glycosylation-inhibiting factor), MIF X68561_at: Sp4 transcription factor, SP4
	Score: 98.91% Genes: Z19554_s_at: vimentin, VIM X03663_at: colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog, CSF1R U90549_at: high mobility group nucleosomal binding domain 4, HMGN4 X67247_rna1_at: ribosomal protein S8, RPS8

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes: U90549_at: high mobility group nucleosomal binding domain 4, HMGN4 M55998_s_at: collagen, type I, alpha 1, COL1A1 Z19554_s_at: vimentin, VIM X13334_at: CD14 antigen, CD14 J04988_at: heat shock 90kDa protein 1, beta, HSPCB X68561_at: Sp4 transcription factor, SP4 L11566_at: ribosomal protein L18, RPL18 S77393_at: Kruppel-like factor 3 (basic), KLF3 L19872_at: aryl hydrocarbon receptor, AHR X73460_at: ribosomal protein L3, RPL3 U68485_at: bridging integrator 1, BIN1 X03663_at: colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog, CSF1R U07231_at: G-rich RNA sequence binding factor 1, GRSF1 M57731_s_at: chemokine (C-X-C motif) ligand 2, CXCL2 X67247_rna1_at: ribosomal protein S8, RPS8 U52696_s_at: cAMP responsive element binding protein-like 1 /// tenascin XB, CREBL1 /// TNXB L19686_rna1_at: macrophage migration inhibitory factor (glycosylation-inhibiting factor), MIF X55715_at: ribosomal protein S3, RPS3 U09937_rna1_s_at: plasminogen activator, urokinase receptor, PLAUR Z49148_s_at: ribosomal protein L29, RPL29