Data set name: GSE468

Brief description:

Our class prediction model for the medulloblastoma data set (GSE468) was built with gene expression profiles of primary medulloblastomas clinically designated as either metastatic (Met) or non-metastatic (NonMet).

Platform: Affymetrix GeneChip Human Cancer Array HC-G110

Diagnostic classes:

- metastatic medulloblastoma (Met): 10 examples (43.5%)

- non-metastatic medulloblastoma (NonMet): 13 examples (56.5%)

Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):

Classification accuracy: 51.67%

Area under curve (AUC): 0.600

	Score: 99.86% Genes: 1818_at 1007_s_at: discoidin domain receptor family, member 1, DDR1 1771_s_at: platelet-derived growth factor receptor, beta polypeptide, PDGFRB 829_s_at: glutathione S-transferase pi, GSTP1 714_at 1380_at: fibroblast growth factor 7 (keratinocyte growth factor), FGF7 1012_at: p300/CBP-associated factor, PCAF 1600_at: TXK tyrosine kinase, TXK
	Score: 99.41% Genes: 1104_s_at: heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B, HSPA1A /// HSPA1B 1818_at 671_at: secreted protein, acidic, cysteine-rich (osteonectin), SPARC 322_at: phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma), PIK3R3 358_at: purinergic receptor P2Y, G-protein coupled, 10, P2RY10 1380_at: fibroblast growth factor 7 (keratinocyte growth factor), FGF7
	Score: 97.48% Genes: 829_s_at: glutathione S-transferase pi, GSTP1 671_at: secreted protein, acidic, cysteine-rich (osteonectin), SPARC 358_at: purinergic receptor P2Y, G-protein coupled, 10, P2RY10 1600_at: TXK tyrosine kinase, TXK

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes: 1380_at: fibroblast growth factor 7 (keratinocyte growth factor), FGF7 1818_at 322_at: phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma), PIK3R3 671_at: secreted protein, acidic, cysteine-rich (osteonectin), SPARC 358_at: purinergic receptor P2Y, G-protein coupled, 10, P2RY10 2062_at: insulin-like growth factor binding protein 7, IGFBP7 205_g_at: homeo box A4, HOXA4 714_at 1600_at: TXK tyrosine kinase, TXK 1693_s_at: tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor), TIMP1 1173_g_at 1104_s_at: heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B, HSPA1A /// HSPA1B 829_s_at: glutathione S-transferase pi, GSTP1 1012_at: p300/CBP-associated factor, PCAF 1127_at: ribosomal protein S6 kinase, 90kDa, polypeptide 1, RPS6KA1 1007_s_at: discoidin domain receptor family, member 1, DDR1 1182_at: phospholipase C-like 1, PLCL1 1771_s_at: platelet-derived growth factor receptor, beta polypeptide, PDGFRB 709_at: tubulin, beta polypeptide, TUBB 1637_at: mitogen-activated protein kinase-activated protein kinase 3, MAPKAPK3